• It feeds on fruit and insects.

The Yucatan pine-like hamster gathers food with its hands and teeth, employing a foraging strategy of searching for food at night on trees and on the ground. The species' diet includes seeds, ripe fruits, coniferous cones, and occasionally small insects, with a daily food requirement ranging from 6 g to 14 g. Among the obtained foods are beetles, butterflies, diptera, hymenoptera, bedbugs, orthoptera, dragonflies, mayflies, and net-winged insects. Yucatan pine-like hamster offspring feed on milk. True skunks, martens, weasels, true vipers, barn owls, western climbing boas, true rattlesnakes, dwarf rattlesnakes, horned owls, and Lesser Asian vipers are predators of this species.