• In captivity it has lived about 2–3 years.
• Litters usually contain 2–4 young.

Chestnut African climbing mice typically live for one to two years, with a theoretical lifespan ranging from one year and eight months to three years and five months. The species reaches sexual maturity between one month and one month and three weeks of age. Development begins with the embryo stage, during which the offspring develops inside the mother. Following this, the young enter the infant stage, where they reside in a nest and are fed milk by the mother for one to three weeks and four days. The adult stage lasts from two months to two years, during which the species can reproduce and independently forage for food.